Health Information – Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP)
JLPP in Rottweilers – FAQ’s
Recently we became aware of an inherited disease in Rottweilers called JLPP (Juvenile Laryngeal Paralysis & Polyneuropathy). As soon as we became aware of this disease many Rottweiler breeders started getting their breeding dogs tested.
How is it inherited?
JLPP is recessive which means that both parents have to be carriers of the JLPP gene in order to produce an affected puppy. If at least one parent is clear then the breeding will not produce an affected puppy. If one parent is a carrier then the breeding will produce both carrier and clear puppies (but no affected). If both parents are clear then the breeding will produce only clear puppies.
Why is it important to test breeding dogs?
It is important to test for this disease as it is always fatal to affected puppies. There is no cure. Symptoms can start to manifest at 12 weeks of age, but, may take longer. Most affected puppies die before 1 year of age. This means that the breeder cannot tell without a DNA test if a puppy is affected before it leaves for its new home at 8 weeks old.
What can I do?
Before buying a Rottweiler puppy make sure at least one of the parents has been tested JLPP clear. For most people (those not looking to breed) it does not matter if one of the parents is a carrier as long as the other is clear.
Do I need to test?
For most the answer is no. Only breeding dogs need to be tested.
If you have any questions about this disease feel free to ask.
(Original text written by Anne-Marie O’Grady)
JLPP FAQ’s for Rottweiler Breeders
Whilst it is not yet compulsory for Rottweiler breeders in Australia to test their breeding dogs for JLPP, it is envisaged that at least at NRCA level it will eventually become compulsory. It is also envisaged that, as with HD/ED results the dog’s microchip number will need to be positively identified when taking DNA samples for testing. Therefore I highly recommend that rather than taking the swab yourself you take your dog/dogs to a vet for the samples to be taken and microchip number to be verified. This way there can be no question of validity, and also ensures your dog’s results will be on the National database.
WHERE CAN I GET MY JLPP TESTS DONE ?
Australia currently do not do the tests, labs in other countries currently testing :
Members of the ANKC who enclose a copy / scan of their membership will discount the set price down to £44.00 per JLPP test (down from £48.00). They are also able to test semen samples if an AI has taken place (from a used vial with some semen residue). It is not guaranteed but some results have already been achieved with this, if successful the charge will be an extra £25.
Laboklin UK has agreed to a “special” discount for those breeders who wish to test litters. For 3+ dogs the test will be 42 pounds. Updates coming soon for procedure on how to test puppies.
Note: this lab accepts other swab kits other than just theirs, so you do not need to wait for theirs to be sent to you – just get your vet to use the swab kits they currently have.
Form to be filled out and sent with swab samples here http://www.laboklin.co.uk/pdf/GeneticTests-DogsCats-B-Form.pdf
OFA website for JLPP testing $65US about $87Aust. http://www.ofa.org/dnatesting/lpp.html
Note: OFA only accept their swab kits, so there is a wait for these to arrive from the US, some 2-4 weeks at the present time.
Once you get your results back from the laboratory, to add your results to the Australian NRCA Database:
email to firstname.lastname@example.org
OR Post to:
The NRCA Breed Recorder, PO Box 1102 Grovedale DC VIC Australia 3216
http://www.nationalrottweilercouncil.com/ Click on Articles
JLPP Australia Facebook page: https://www.facebook.com/groups/JLPPinRottweilers/